Path of Exile 2 Currency Farming Guide: The Sanctum Spotlight

Welcome to the world of Path of Exile 2 Currency farming! In this guide, we will be focusing on The Trial of the Seamas, commonly referred to as Sanctum, which serves as the first Ascendancy trial in Path of Exile 2. Not only does it test your character’s capabilities, but it is also an incredibly efficient method for generating currency. If you’re here specifically for the currency farming strategies, let’s dive right in!

Should You Farm Sanctum?

The first question to ask is: should you farm Sanctum? The short answer is yes, but there are several factors to consider before committing to it as your primary farming method.

1. Is Your Build Fast?

Sanctum requires traversing a large amount of ground quickly. Having a fast build significantly increases efficiency. Builds like Stat-Stacking Tempest Flurry, Queen of the Forest, or Temporal Chains setups excel in this environment. While you can still run Sanctum without these builds, a slower character will limit your farming efficiency and strategy options.

2. Is Your Build Strong?

Your build’s overall strength only becomes a concern when fighting Zarok, the final boss of Sanctum. While immense strength isn’t necessary, it does provide flexibility in farming methods. If you are confident in your boss-killing ability, you can utilize more aggressive relic setups.

3. Can You Afford the Startup Costs?

Running Sanctum profitably requires investing in relic setups. These can range anywhere from 1 to 25+ Divines, depending on the setup. Understanding relics and their optimal combinations is key to maximizing profits.

How to Make Currency in Sanctum

There are three main ways to earn currency while farming Sanctum:

• Magic Relics

• Unique Relics

• Jewels

Let’s go over each of these in detail.

Magic Relics

Magic relics are the most common items you’ll find in Sanctum. They drop from monsters, chests, and can even be purchased from NPCs. To ensure you get the highest-tier affixes, always run a level 80+ Sanctum.

The most valuable magic relics include:

• Seals & Tapestries – Look for modifiers like:

  • Increased Quantity of Relics (most important)

  • Increased Maximum Life/Defenses/Honor

  • Increased Movement Speed

• Mforas – These should have:

  • Additional Merchant Choices

  • Reduced Merchant Prices

If a relic has only one of these modifiers at max value, consider using an Annulment Orb and Augmentation Orb to try and get the second modifier.

Additional Valuable Relics

• Seals & Urns with:

  • Traps Deal Reduced Damage

  • +Meters to Dodge Roll Distance

  • High Quantity of Relics Modifier

If you find any other valuable relics, share them with the community!

Unique Relics

Unique relics are much simpler to handle. The two primary ones to look for are:

• Desperate Alliance Vase Relic

• Last Flame Incense Relic

These only drop from Zarok, with the following drop rates:

• Desperate Alliance – ~15% drop rate, worth ~2.5 Divines

• Last Flame – ~0.5% drop rate, worth ~330 Divines

Your relic setup determines how many unique relics you get per Zarok kill, which we’ll cover in the relic strategy section.

Jewels

There are four primary jewel types to farm in Sanctum:

1. Standard Magic & Rare Jewels

2. Magic & Rare Time-Lost Jewels

3. Unique Grand Spectrum Jewels

4. Unique “Against the Darkness” Time-Lost Jewels

Jewels drop from caches, particularly Gold Caches. Therefore, collecting Gold Keys is essential to maximize profits.

Valuing and Selling Jewels

• Regular Magic Jewels – Some of the most expensive jewels in the game can be Magic-tier, so do not Regal them.

• Grand Spectrum Jewels:

  • Rubies – Not valuable

  • Emeralds – ~0.5 Divines

  • Sapphires – ~9 Divines

• Grand Spectrum caches appear 1 in 15 runs, so hope for a Sapphire when they do.

• Against the Darkness Jewels (ATDs):

  • Unidentified ATDs sell for ~4-5 Divines

  • Identified ATDs range from 90 Exalts to hundreds of Divines

If you want consistent profit, sell ATDs unidentified. Identifying them is a gamble, only recommended if you can afford potential losses.

Relic Strategies

Relic setups dictate how much currency you make from Sanctum. There isn’t a one-size-fits-all setup, so we use a Relic Flowchart to optimize efficiency.

1. Prioritizing Comfort

Farming efficiently means minimizing friction. Focus on:

• Increasing Honor (more mistakes allowed)

• Boosting Movement Speed (faster runs)

• Enhancing Damage (easier boss fights)

• Utilizing Merchant Strategy (extra rewards)

2. Maximizing Relic Quantity

Once your runs are smooth, prioritize stacking Quantity of Relics. The higher the relic quantity, the greater the profits.

3. Desperate Alliance Relic Considerations

Running the Desperate Alliance Relic means:

• Zarok becomes much harder

• Requires 4 vertical slots in your setup

• Guarantees an “Against the Darkness” jewel

If you struggle with Zarok, consider dropping some currency-boosting relics in favor of survivability.

Profitability Breakdown

Since profits depend on RNG, Sanctum doesn’t have a fixed Divines per hour rate. However, here’s a rough breakdown:

• Low Playtime Players:

  • Potential Jackpot: A single Last Flame drop can set up your entire build.

• Steady Profit Farmers:

  • Running Desperate Alliance and selling unidentified ATDs yields ~2 Divines per run.

If you’re lucky and get valuable magic relics or a Last Flame, your profit skyrockets.

Final Thoughts

Sanctum is one of the best currency farming methods in Path of Exile 2. Whether you’re looking for consistent profits or hoping for a massive jackpot, Sanctum provides both opportunities or buy POE2 Currency.

To summarize:

• Fast builds = better efficiency

• Magic relics, unique relics, and jewels generate profit

• Desperate Alliance Relic offers steady earnings

• Identifying ATDs is risky but profitable if lucky

• Gold keys and caches significantly impact loot quality

If you’re looking for an engaging and profitable way to farm in Path of Exile 2, Sanctum is an excellent choice. Happy farming, Exiles!